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« Week of April 8, 2012 »
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Start: 04/09/2012 10:00 am
End: 04/09/2012 12:00 pm

The genomic diversity of viral quasispecies is a subject of great interest, especially for chronic infections. Characterization of viral diversity can be addressed by high-throughput sequencing technology (454 Life Sciences, Illumina, SOLiD, Ion Torrent, etc). Standard assembly software was originally designed for single-genome assembly and cannot be used to assemble and estimate the frequency of closely related quasispecies sequences. This work develops parsimonious and maximum likelihood models for assembling viral quasispecies and estimating their frequencies from 454 sequencing data.

10
Start: 04/10/2012 2:00 pm
End: 04/10/2012 3:00 pm

Understanding biology at the system level has gained much more interest recently due to the rapid development in genome sequencing and high-throughput measurements. Mathematical descriptions of biological systems are normally formalized using two different approaches. The deterministic method is very efficient at predicting the overall behavior of the system but ignores the inherent fluctuations and correlations at lower concentration. The stochastic method, on the other hand, captures the intrinsic randomness but is often mathematically intractable and computationally expensive.

11
Start: 04/11/2012 11:00 am
End: 04/11/2012 12:00 pm

Parallel processing and parallel programming concepts are currently focused on the senior and graduate college levels of Computer Science and Information Technology educational curriculums, even though they are playing a bigger and bigger role in all types of new system and software designs. My project aims to teach parallel processing concepts to earlier students (preferably high school and early college) of the engineering and computing fields. The basic concepts of parallelism are introduced in a video-game environment.

12
Start: 04/12/2012 3:00 pm
End: 04/12/2012 4:00 pm

SAFOD (San Andreas Fault Observatory at Depth) is a deep-drilling component of EarthScope that is trying to determine the reasons for faults within volcanic rock, which is a point of generation for earthquakes. This project resulted in the accumulation of a large quantity of information that needs to be organized and connected. SAFOD BM2KB aims to provide the scientific community with a knowledge base of current and past findings of research groups about the microstructures and mechanics of brittle faulting from SAFOD cores.

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